Hypothyroidism medication prices (2026)
Hypothyroidism is treated with levothyroxine (Synthroid). Generic levothyroxine is one of the most commonly prescribed drugs in the US, typically under $10/month cash.
Medically reviewed by Sara Marin, PharmD · Last verified 2026-05-18
All Hypothyroidism medications ranked by cash price
| Brand | Generic | Strength | Generic cash | Brand cash |
|---|---|---|---|---|
| Synthroid | Levothyroxine | 100 mcg | $9.10 | $52.00 |
| Cytomel | Liothyronine | 25 mcg | $18.40 | $78.00 |
FAQ
What is the cheapest medication for Hypothyroidism?
Generic Levothyroxine (Synthroid) averages $9.10 cash. Cost Plus and Costco usually have the lowest verified prices.
Can I fill Hypothyroidism medications without insurance?
Yes. Every drug on this page can be filled cash-pay at any US pharmacy. Generic versions are usually under $15/month at Cost Plus, Costco, or with a GoodRx coupon.
Are generic Hypothyroidism drugs as good as brand?
Yes — the FDA requires generics to contain the same active ingredient at the same strength as the brand and to be therapeutically equivalent.