Type 2 Diabetes medication prices (2026)
Type 2 diabetes is treated with oral medications (metformin, sulfonylureas, DPP-4 inhibitors, SGLT2 inhibitors) and injectable GLP-1 agonists. Cash prices for older generics like metformin are under $10/month; brand GLP-1s like Ozempic and Mounjaro can exceed $1,000/month without insurance.
Medically reviewed by Sara Marin, PharmD · Last verified 2026-05-18
All Diabetes medications ranked by cash price
| Brand | Generic | Strength | Generic cash | Brand cash |
|---|---|---|---|---|
| Glucophage | Metformin | 500 mg | $4.00 | $89.00 |
| Amaryl | Glimepiride | 2 mg | $4.80 | $68.00 |
| Glucotrol | Glipizide | 10 mg | $5.40 | $72.00 |
| Actos | Pioglitazone | 30 mg | $12.40 | $148.00 |
| Lantus | Insulin Glargine | 100 units/mL | $68.00 | $284.00 |
| Levemir | Insulin Detemir | 100 units/mL | $72.00 | $289.00 |
| Humalog | Insulin Lispro | 100 units/mL | $78.50 | $332.00 |
| NovoLog | Insulin Aspart | 100 units/mL | $82.00 | $328.00 |
| Januvia | Sitagliptin | 100 mg | $289.00 | $612.00 |
| Farxiga | Dapagliflozin | 10 mg | $592.00 | $612.00 |
| Jardiance | Empagliflozin | 25 mg | $628.00 | $648.00 |
| Victoza | Liraglutide | 1.8 mg/dose | $780.00 | $812.00 |
| Trulicity | Dulaglutide | 1.5 mg/dose | $860.00 | $892.00 |
| Ozempic | Semaglutide | 1 mg/dose | $920.00 | $968.00 |
| Mounjaro | Tirzepatide | 5 mg/dose | $1020.00 | $1069.00 |
FAQ
What is the cheapest medication for Diabetes?
Generic Metformin (Glucophage) averages $4.00 cash. Cost Plus and Costco usually have the lowest verified prices.
Can I fill Diabetes medications without insurance?
Yes. Every drug on this page can be filled cash-pay at any US pharmacy. Generic versions are usually under $15/month at Cost Plus, Costco, or with a GoodRx coupon.
Are generic Diabetes drugs as good as brand?
Yes — the FDA requires generics to contain the same active ingredient at the same strength as the brand and to be therapeutically equivalent.