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Price comparison only — not medical advice. Always confirm with your pharmacist. Terms

Seasonal Allergies medication prices (2026)

Second-generation antihistamines (loratadine, cetirizine, fexofenadine) and nasal steroids (fluticasone, mometasone) are first-line for seasonal allergies. All are available OTC for $5–15.

Medically reviewed by Sara Marin, PharmD · Last verified 2026-05-18

Cheapest right now

Benadryl

Generic Diphenhydramine averages $3.40 cash

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All Allergies medications ranked by cash price

BrandGenericStrengthGeneric cashBrand cash
BenadrylDiphenhydramine25 mg$3.40$11.99
ZyrtecCetirizine10 mg$6.20$18.99
ClaritinLoratadine10 mg$6.50$19.99
AllegraFexofenadine180 mg$7.10$21.99
SingulairMontelukast10 mg$7.40$178.00
FlonaseFluticasone Nasal50 mcg$8.40$22.99
NasonexMometasone Nasal50 mcg$18.40$212.00

FAQ

What is the cheapest medication for Allergies?

Generic Diphenhydramine (Benadryl) averages $3.40 cash. Cost Plus and Costco usually have the lowest verified prices.

Can I fill Allergies medications without insurance?

Yes. Every drug on this page can be filled cash-pay at any US pharmacy. Generic versions are usually under $15/month at Cost Plus, Costco, or with a GoodRx coupon.

Are generic Allergies drugs as good as brand?

Yes — the FDA requires generics to contain the same active ingredient at the same strength as the brand and to be therapeutically equivalent.

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