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Cognitive / Nootropic
Semax
ACTH(4-10) analog
A synthetic heptapeptide developed in Russia and listed as a stroke-recovery medicine on the Russian Vital and Essential Drugs list.
Compounded · 503A Pharmacy
Mechanism of action
Increases brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) expression while modulating dopamine and serotonin turnover.
Studied uses
- ✓Cognitive enhancement & focus
- ✓Neuroprotection after ischemic events
- ✓ADHD support (off-label)
- ✓Stress resilience
Research highlights
- · Approved in Russia for ischemic stroke
- · Multiple Russian-language trials in cognitive disorders
- · Limited Western clinical replication
Side effects & cautions
- · Mild nasal irritation
- · Headache at higher doses
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