Free shipping on orders over $15012% off your first order — code FIRST12Stack 3+ peptides, save 20% with STACK20US 503A partner pharmacy · Cold-chain shipped
Free shipping on orders over $15012% off your first order — code FIRST12Stack 3+ peptides, save 20% with STACK20US 503A partner pharmacy · Cold-chain shipped
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Mitochondrial / Metabolic

MOTS-c

Mitochondrial-derived peptide

A 16-amino-acid peptide encoded within mitochondrial DNA — a master regulator of metabolic homeostasis.

MOTS-c

Compounded · 503A Pharmacy

Mechanism of action

Activates AMPK signaling, enhancing glucose uptake and fatty-acid oxidation while suppressing the methionine-folate cycle.

Studied uses

  • Insulin sensitivity & metabolic health
  • Exercise performance & VO₂ max
  • Healthy aging support
  • Body-composition optimization

Research highlights

  • · Reverses age-dependent insulin resistance in mice
  • · Increases physical capacity in aged murine models
  • · Levels decline with age in human plasma

Side effects & cautions

  • · Transient fatigue post-injection
  • · Limited human trial data