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Anti-Inflammatory
KPV
Lysine-Proline-Valine
A potent C-terminal fragment of alpha-MSH with broad anti-inflammatory and antimicrobial activity.
Compounded · 503A Pharmacy
Mechanism of action
Acts intracellularly to suppress NF-κB signaling and downregulate pro-inflammatory cytokines like TNF-α and IL-1β.
Studied uses
- ✓Inflammatory bowel disease (IBD) support
- ✓Skin conditions (eczema, psoriasis)
- ✓Mast cell activation calming
- ✓Wound healing
Research highlights
- · Reduces colonic inflammation in murine colitis models
- · Antimicrobial activity against S. aureus and C. albicans
- · Stable, non-immunogenic tripeptide
Side effects & cautions
- · Excellent safety profile in preclinical work
- · Rare reports of flushing
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