← All peptides
Cognitive / Neuroregenerative
DiHexa
Angiotensin IV analog
A small-molecule angiotensin IV analog reported to be ~7 orders of magnitude more potent than BDNF at promoting synaptogenesis.
Compounded · 503A Pharmacy
Mechanism of action
Augments hepatocyte growth factor (HGF) / c-Met signaling, driving formation of new functional synapses.
Studied uses
- ✓Cognitive performance & memory
- ✓Neurodegenerative disease research
- ✓Recovery from traumatic brain injury
Research highlights
- · Restored cognitive function in aged & scopolamine-impaired rats
- · Active orally — rare for a peptide
Side effects & cautions
- · Headache, restlessness at higher doses
- · Limited human safety data — caution warranted
Other peptides
BPC-157
A 15-amino-acid fragment of a protective protein found in human gastric juice — the most widely used therapeutic peptide in the world.
KPV
A potent C-terminal fragment of alpha-MSH with broad anti-inflammatory and antimicrobial activity.
TB-500
A synthetic fragment of Thymosin Beta-4 that promotes tissue repair, cell migration, and reduction of fibrosis.