How much does Wellbutrin XL cost without insurance?

Wellbutrin XL (Bupropion) 300 mg costs around $18.40 cash for the generic and $398.00 for the brand. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Wellbutrin XL?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Bupropion. CVS and Walgreens are the most expensive. Exact rankings update live above.

Which pharmacy has the cheapest Wellbutrin XL in 2026?

Mark Cuban Cost Plus currently has the lowest verified cash price for Wellbutrin XL (Bupropion) at $10.12. Cost Plus Drugs and Costco are consistently the cheapest US pharmacies for most generics.

Is CVS or Walgreens cheaper for Wellbutrin XL?

Neither — both are typically 30–60% more expensive than Cost Plus or Costco. CVS and Walgreens consistently rank as the most expensive cash-pay pharmacies for Bupropion.

How often do these prices change?

Tuesdays refreshes prices at minimum every 72 hours from public retail price feeds. Mail-order partners like Cost Plus and Amazon Pharmacy can change daily.

Mental Health

Wellbutrin XL

Name: Wellbutrin XL 300 mg (Bupropion)
Brand: Wellbutrin XL
SKU: wellbutrin-xl
Availability: InStock

Bupropion · 300 mg · tablet · qty 30

NDRI; depression, smoking cessation.

Medically reviewed by Sara Marin, PharmD · Last verified 2026-05-18

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Price summary

Form	Class	Brand avg	Generic avg	Savings
tablet 300 mg	Rx	$398.00	$18.40	95%

FAQ

Is generic Bupropion the same as Wellbutrin XL?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $379.60 per fill (95% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on Tuesdays are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.