How much does Effexor XR cost without insurance?

Effexor XR (Venlafaxine) 75 mg costs around $12.20 cash for the generic and $312.00 for the brand. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Effexor XR?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Venlafaxine. CVS and Walgreens are the most expensive. Exact rankings update live above.

How does a Effexor XR discount card work?

Show the discount card barcode to your pharmacist at checkout. They run it instead of insurance, and the cash price is reduced. No signup, no email, no insurance card needed.

Is the Effexor XR discount card really free?

Yes — the GoodRx card is free forever. Tuesdays makes no money on coupons. We also compare the card price to direct cash prices at Cost Plus and Costco, which are sometimes lower.

Mental Health

Effexor XR

Name: Effexor XR 75 mg (Venlafaxine)
Brand: Effexor XR
SKU: effexor-xr
Availability: InStock

Venlafaxine · 75 mg · capsule · qty 30

SNRI for depression, anxiety.

Medically reviewed by Sara Marin, PharmD · Last verified 2026-05-18

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Price summary

Form	Class	Brand avg	Generic avg	Savings
capsule 75 mg	Rx	$312.00	$12.20	96%

FAQ

Is generic Venlafaxine the same as Effexor XR?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $299.80 per fill (96% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on Tuesdays are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.