How much does Desyrel cost without insurance?

Desyrel (Trazodone) 50 mg costs around $4.20 cash for the generic and $78.00 for the brand. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Desyrel?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Trazodone. CVS and Walgreens are the most expensive. Exact rankings update live above.

Which pharmacy has the cheapest Desyrel in 2026?

Mark Cuban Cost Plus currently has the lowest verified cash price for Desyrel (Trazodone) at $2.31. Cost Plus Drugs and Costco are consistently the cheapest US pharmacies for most generics.

Is CVS or Walgreens cheaper for Desyrel?

Neither — both are typically 30–60% more expensive than Cost Plus or Costco. CVS and Walgreens consistently rank as the most expensive cash-pay pharmacies for Trazodone.

How often do these prices change?

Tuesdays refreshes prices at minimum every 72 hours from public retail price feeds. Mail-order partners like Cost Plus and Amazon Pharmacy can change daily.

Mental Health

Desyrel

Name: Desyrel 50 mg (Trazodone)
Brand: Desyrel
SKU: desyrel
Availability: InStock

Trazodone · 50 mg · tablet · qty 30

Off-label sleep, depression.

Medically reviewed by Sara Marin, PharmD · Last verified 2026-05-18

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Price summary

Form	Class	Brand avg	Generic avg	Savings
tablet 50 mg	Rx	$78.00	$4.20	95%

FAQ

Is generic Trazodone the same as Desyrel?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $73.80 per fill (95% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on Tuesdays are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.