How much does Enbrel cost without insurance?

Enbrel (Etanercept) 50 mg/mL averages $7128.00 cash with no FDA-approved generic available. Live prices on this page update at least every 72 hours.

What pharmacy has the cheapest Enbrel?

Mail-order pharmacies and the manufacturer savings card typically offer the lowest cash cost for Enbrel. Exact rankings update live above.

Which pharmacy has the cheapest Enbrel in 2026?

Costco Pharmacy currently has the lowest verified cash price for Enbrel (Etanercept) at $4240.80. Cost Plus Drugs and Costco are consistently the cheapest US pharmacies for most generics.

Is CVS or Walgreens cheaper for Enbrel?

Neither — both are typically 30–60% more expensive than Cost Plus or Costco. CVS and Walgreens consistently rank as the most expensive cash-pay pharmacies for Etanercept.

How often do these prices change?

Tuesdays refreshes prices at minimum every 72 hours from public retail price feeds. Mail-order partners like Cost Plus and Amazon Pharmacy can change daily.

Specialty

Enbrel

Name: Enbrel 50 mg/mL (Etanercept)
Brand: Enbrel
SKU: enbrel
Availability: InStock

Active ingredient: Etanercept · 50 mg/mL · pen · qty 4

No FDA-approved generic available — manufacturer savings card may cut cost 50%+

Autoimmune (RA, psoriasis).

Medically reviewed by Sara Marin, PharmD · Last verified 2026-05-18

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Price summary

Form	Class	Brand avg	Generic avg	Savings
pen 50 mg/mL	Specialty	$7128.00	$6840.00	4%

FAQ

Is there a generic for Enbrel?

Not yet. The FDA has not approved a generic equivalent for Enbrel (Etanercept). A manufacturer savings card from the brand maker is usually the largest legitimate discount available today.

How much can I save by choosing the generic?

Currently no FDA-approved generic equivalent exists for Enbrel, so the brand and generic prices are similar.

Do I need insurance to get this price?

No. The prices shown on Tuesdays are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.