How much does Advair Diskus cost without insurance?

Advair Diskus (Fluticasone/Salmeterol) 250/50 mcg costs around $178.00 cash for the generic and $412.00 for the brand. Live prices on this page are verified within the last 72 hours.

What pharmacy has the cheapest Advair Diskus?

Cost Plus Drugs and Costco typically have the lowest cash price for generic Fluticasone/Salmeterol. CVS and Walgreens are the most expensive. Exact rankings update live above.

Is there a real Advair Diskus coupon?

Yes. The GoodRx coupon for Fluticasone/Salmeterol is free and accepted at most US pharmacies. We also show the cash price at Cost Plus and Costco, which is often lower than any coupon.

Do I need to sign up to use the Advair Diskus coupon?

No. The GoodRx coupon is free and works without an account. Show it to the pharmacist at the counter — no insurance, no signup, no email.

What is the cash price for Advair Diskus without a coupon?

Cash price for generic Fluticasone/Salmeterol averages $178.00 at Cost Plus, 201.14 at Costco. Brand averages $412.00.

Asthma / COPD

Advair Diskus

Name: Advair Diskus 250/50 mcg (Fluticasone/Salmeterol)
Brand: Advair Diskus
SKU: advair
Availability: InStock

Fluticasone/Salmeterol · 250/50 mcg · inhaler · qty 1

Long-term asthma & COPD maintenance.

Medically reviewed by Sara Marin, PharmD · Last verified 2026-05-18

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Price summary

Form	Class	Brand avg	Generic avg	Savings
inhaler 250/50 mcg	Specialty	$412.00	$178.00	57%

FAQ

Is generic Fluticasone/Salmeterol the same as Advair Diskus?

Yes. The FDA requires generics to contain the same active ingredient at the same strength as the brand. Inactive ingredients (binders, dyes) may differ.

How much can I save by choosing the generic?

On average $234.00 per fill (57% off the brand price). Savings vary by pharmacy — see live prices above.

Do I need insurance to get this price?

No. The prices shown on Tuesdays are cash prices. Often these beat insurance copays for generics.

How often is this price updated?

At minimum every 72 hours. Many sources refresh every few hours.

Related drugs

Symbicort
Budesonide/Formoterol
$182.00

Other drugs for Asthma

Cheapest Advair Diskus alternatives

Symbicort — $182.00

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Advair Diskus vs Symbicort

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Information for general comparison only. Not medical advice. Confirm with your pharmacist.