NDRI antidepressantGeneric available
Bupropion
Sold as Wellbutrin, Wellbutrin XL, Zyban
Bupropion is a norepinephrine-dopamine reuptake inhibitor used for depression, seasonal affective disorder, and smoking cessation. Generally weight-neutral and without sexual side effects.
Compare prices →~$18.00 / mo (generic, NADAC)
What it treats
Depression, seasonal affective disorder, smoking cessation.
Typical dosing
Wellbutrin XL: 150–300 mg once daily in the morning.
Side effects
Insomnia, dry mouth, headache, decreased appetite. Lowers seizure threshold.
Interactions to know
Avoid in patients with seizure disorders, eating disorders, or abrupt alcohol/benzo withdrawal.
Pregnancy & breastfeeding
Risk-benefit discussion.
Educational only. Not medical advice. Always confirm with your prescriber or pharmacist.